Protein C11orf54

1 protein

1.1 primary sequence
1.2 secondary structure
1.3 subcellular localization
1.4 expression & post translational modifications

protein
primary sequence

table 2 shows different characteristics of protein sequence throughout humans , other orthologs.}}</ref>

secondary structure

the protein of c11orf54 exists monomer in solution. protein assumes globular shape of 20 beta strands , 4 alpha helices, containing 9 antiparallel beta strands forming beta screw region. β-screw region of c11orf54 has structural similarity cyclic adenosine 3′,5′-monophosphate (camp) binding domain of regulatory subunit of protein kinase a. zinc ion bound hxhxxxxxxxxxh motif found in sequence.

subcellular localization

c11orf54 predicted localized 60.9% in cytoplasm, 21.7% in nucleus, 13.0% mitochondrial , 4.3% in golgi apparatus.

expression & post translational modifications

image 1: post-transcriptional modifications c11orf54 protein

see image one. protein highly expressed in kidneys , moderately expressed in adrenal gland, colon, liver, testis , thyroid gland.